| Round | Pick | Team | Position | First | Last | Player ID |
|---|
| ROUND 1 |
| 1 | 1 | Philadelphia | WR | Michael | Crabtree | |
| 1 | 2 | Washington | QB | Matthew | Stafford | |
| 1 | 3 | Denver | LB | Brian | Cushing | |
| 1 | 4 | Houston | LB | James | Laurinaitis | |
| 1 | 5 | Cleveland | S | Patrick | Chung | |
| 1 | 6 | Dallas | T | Jason | Smith | |
| 1 | 7 | Pittsburgh | T | Eugene | Monroe | |
| 1 | 8 | Philadelphia | WR | Percy | Harvin | |
| 1 | 9 | New England | DT | B.J. | Raji | |
| 1 | 10 | Green Bay | LB | Clint | Sintim | |
| 1 | 11 | Tampa Bay | CB | Alphonso | Smith | |
| 1 | 12 | Tampa Bay | CB | Vontae | Davis | |
| 1 | 13 | Tampa Bay | DE | Tyson | Jackson | |
| 1 | 14 | Baltimore | HB | Knowshon | Moreno | |
| 1 | 15 | Oakland | DT | Evander | Hood | |
| 1 | 16 | San Francisco | DE | Robert | Ayers | |
| 1 | 17 | New York N | HB | Chris | Wells | |
| 1 | 18 | Buffalo | CB | Jairus | Byrd | |
| ROUND 2 |
| 2 | 1 | Carolina | FB | Jason | Cook | |
| 2 | 2 | Washington | WR | Kenny | Britt | |
| 2 | 3 | Denver | T | Eben | Britton | |
| 2 | 4 | Houston | DE | Brian | Orakpo | |
| 2 | 5 | Detroit | S | William | Moore | |
| 2 | 6 | Dallas | DE | Connor | Barwin | |
| 2 | 7 | Pittsburgh | DT | Alex | Magee | |
| 2 | 8 | Carolina | CB | Ryan | Mouton | |
| 2 | 9 | New England | C | Alex | Mack | |
| 2 | 10 | Green Bay | CB | Sean | Smith | |
| 2 | 11 | Buffalo | LB | Cody | Brown | |
| 2 | 12 | Tampa Bay | S | Rashad | Johnson | |
| 2 | 13 | Detroit | CB | Derek | Cox | |
| 2 | 14 | Baltimore | QB | Josh | Freeman | |
| 2 | 15 | Oakland | G | Louis | Vasquez | |
| 2 | 16 | San Francisco | LB | Dannell | Ellerbe | |
| 2 | 17 | New York N | G | Nick | Hennessey | |
| 2 | 18 | Buffalo | WR | Pat | White | |
| ROUND 3 |
| 3 | 1 | Buffalo | CB | Asher | Allen | |
| 3 | 2 | Oakland | LB | DeAndre | Levy | |
| 3 | 3 | Denver | DE | Ryan | Baker | |
| 3 | 4 | Houston | LB | Kaluka | Maiava | |
| 3 | 5 | Detroit | LB | Ashlee | Palmer | |
| 3 | 6 | Dallas | WR | Derrick | Williams | |
| 3 | 7 | Pittsburgh | G | Duke | Robinson | |
| 3 | 8 | Carolina | WR | Quan | Cosby | |
| 3 | 9 | New England | G | Mark | Lewis | |
| 3 | 10 | Green Bay | TE | Brandon | Pettigrew | |
| 3 | 11 | Buffalo | CB | Christopher | Owens | |
| 3 | 12 | Tampa Bay | DT | Corvey | Irvin | |
| 3 | 13 | Detroit | HB | Mike | Goodson | |
| 3 | 14 | Baltimore | WR | Tyree | Barnes | |
| 3 | 15 | Oakland | TE | Jared | Cook | |
| 3 | 16 | San Francisco | T | Sebastian | Vollmer | |
| 3 | 17 | New York N | S | Chip | Vaughn | |
| 3 | 18 | Tampa Bay | DE | Henry | Melton | |
| ROUND 4 |
| 4 | 1 | Carolina | TE | J'Nathan | Bullock | |
| 4 | 2 | Washington | S | Emanuel | Cook | |
| 4 | 3 | Denver | QB | Tom | Brandstater | |
| 4 | 4 | Houston | DE | Will | Johnson | |
| 4 | 5 | Detroit | T | Robert | Brewster | |
| 4 | 6 | Buffalo | HB | Shonn | Greene | |
| 4 | 7 | Pittsburgh | WR | Patrick | Turner | |
| 4 | 8 | Carolina | S | Keith | Fitzhugh | |
| 4 | 9 | New England | T | Seth | Olsen | |
| 4 | 10 | Green Bay | QB | Rhett | Bomar | |
| 4 | 11 | Baltimore | WR | Austin | Collie | |
| 4 | 12 | Tampa Bay | DT | Fili | Moala | |
| 4 | 13 | Detroit | WR | Brennan | Marion | |
| 4 | 14 | Baltimore | C | Max | Unger | |
| 4 | 15 | Oakland | HB | Aaron | Brown | |
| 4 | 16 | San Francisco | FB | Tony | Fiammetta | |
| 4 | 17 | New York N | G | Rich | Ohrnberger | |
| 4 | 18 | Baltimore | HB | Gartrell | Johnson | |
| ROUND 5 |
| 5 | 1 | Philadelphia | G | Colin | Dow | |
| 5 | 2 | Philadelphia | FB | Quinn | Johnson | |
| 5 | 3 | Denver | CB | D.J. | Moore | |
| 5 | 4 | Houston | T | Jamon | Meredith | |
| 5 | 5 | Cleveland | G | J.D. | Quinn | |
| 5 | 6 | Dallas | LB | Tony | Fein | |
| 5 | 7 | Pittsburgh | K | David | Buehler | |
| 5 | 8 | Carolina | DT | Louis | Ellis | |
| 5 | 9 | New England | CB | Jamarca | Love | |
| 5 | 10 | Green Bay | S | Troy | Nolan | |
| 5 | 11 | New York N | HB | Javon | Ringer | |
| 5 | 12 | Tampa Bay | TE | Jared | Bronson | |
| 5 | 13 | Detroit | CB | K.J. | Gerard | |
| 5 | 14 | Baltimore | DT | Terrance | Knighton | |
| 5 | 15 | Oakland | CB | Morgan | Trent | |
| 5 | 16 | San Francisco | WR | Rico | Murray | |
| 5 | 17 | New York N | WR | Mike | Wallace | |
| 5 | 18 | Baltimore | S | Tom | Nelson | |
| ROUND 6 |
| 6 | 1 | Philadelphia | LB | Garrison | Sanborn | |
| 6 | 2 | Washington | LB | Jasper | Brinkley | |
| 6 | 3 | Denver | DT | Ventrell | Jenkins | |
| 6 | 4 | Houston | TE | Travis | Beckum | |
| 6 | 5 | Cleveland | LB | Stanley | Arnoux | |
| 6 | 6 | Dallas | QB | Brian | Hoyer | |
| 6 | 7 | Pittsburgh | WR | Demetrius | Byrd | |
| 6 | 8 | Carolina | C | Robby | Felix | |
| 6 | 9 | New England | FB | Rashad | Jennings | |
| 6 | 10 | Green Bay | LB | Cody | Glenn | |
| 6 | 11 | Baltimore | DT | Vaughn | Martin | |
| 6 | 12 | Tampa Bay | G | Jaimie | Thomas | |
| 6 | 13 | Detroit | WR | Juaquin | Iglesias | |
| 6 | 14 | Baltimore | WR | Britt | Davis | |
| 6 | 15 | Oakland | DE | Michael | Johnson | |
| 6 | 16 | San Francisco | LB | William | VanDetrSteeg | |
| 6 | 17 | New York N | WR | Kenny | McKinley | |
| 6 | 18 | Detroit | CB | Vontae | Davis | |
| ROUND 7 |
| 7 | 1 | Philadelphia | DE | Orion | Martin | |
| 7 | 2 | Washington | HB | Marlon | Lucky | |
| 7 | 3 | Denver | FB | Eric | Kettani | |
| 7 | 4 | Houston | S | Michael | Hamlin | |
| 7 | 5 | Cleveland | QB | Keith | Null | |
| 7 | 6 | Dallas | DT | Myron | Pryor | |
| 7 | 7 | Pittsburgh | TE | John | Nalbone | |
| 7 | 8 | Detroit | LB | Gerald | McRath | |
| 7 | 9 | New England | K | Pat | McAfee | |
| 7 | 10 | Cleveland | LB | Dan | Skuta | |
| 7 | 11 | New York A | WR | Greg | Orton | |
| 7 | 12 | Tampa Bay | HB | Anthony | Kimble | |
| 7 | 13 | Detroit | WR | Brooks | Foster | |
| 7 | 14 | Baltimore | T | Garrett | Reynolds | |
| 7 | 15 | Oakland | G | Lance | Louis | |
| 7 | 16 | San Francisco | TE | Darrius | Hill | |
| 7 | 17 | New York N | WR | David | Richmond | |
| 7 | 18 | New York A | CB | Brandon | Hughes | |