| Round | Pick | Team | Position | First | Last | Player ID |
|---|
| ROUND 1 |
| 1 | 1 | Seattle | QB | Cam | Newton | |
| 1 | 2 | St. Louis | HB | DeMarco | Murray | |
| 1 | 3 | Baltimore | WR | Julio | Jones | |
| 1 | 4 | Denver | LB | Akeem | Ayers | |
| 1 | 5 | Dallas | CB | Prince | Amukamara | |
| 1 | 6 | Washington | CB | Ras-I | Dowling | |
| 1 | 7 | Kansas City | CB | Aaron | Williams | |
| 1 | 8 | Washington | S | Quinton | Carter | |
| 1 | 9 | Green Bay | T | Anthony | Castonzo | |
| 1 | 10 | Indianapolis | CB | Curtis | Brown | |
| 1 | 11 | San Francisco | DT | Nick | Fairley | |
| 1 | 12 | Miami | LB | Bruce | Carter | |
| 1 | 13 | Oakland | LB | Dontay | Moch | |
| 1 | 14 | Baltimore | WR | Denarius | Moore | |
| 1 | 15 | Jacksonville | DE | Ryan | Kerrigan | |
| 1 | 16 | San Diego | WR | Edmund | Gates | |
| 1 | 17 | Miami | DE | Cameron | Jordan | |
| 1 | 18 | Miami | CB | Josh | Thomas | |
| ROUND 2 |
| 2 | 1 | Seattle | CB | Chimdi | Chekwa | |
| 2 | 2 | St. Louis | WR | Jon | Baldwin | |
| 2 | 3 | Baltimore | T | Nate | Solder | |
| 2 | 4 | Denver | WR | Titus | Young | |
| 2 | 5 | Dallas | DE | Aldon | Smith | |
| 2 | 6 | Detroit | DE | Ricky | Elmore | |
| 2 | 7 | Kansas City | DT | Phil | Taylor | |
| 2 | 8 | Kansas City | LB | Jonas | Mouton | |
| 2 | 9 | San Francisco | LB | K.J. | Wright | |
| 2 | 10 | Indianapolis | QB | Christian | Ponder | |
| 2 | 11 | San Francisco | G | John | Bender | |
| 2 | 12 | New York A | HB | Roy | Helu | |
| 2 | 13 | Detroit | LB | Eric | McBride | |
| 2 | 14 | Kansas City | T | Orlando | Franklin | |
| 2 | 15 | Jacksonville | G | Danny | Watkins | |
| 2 | 16 | San Diego | CB | Johnny | Patrick | |
| 2 | 17 | Oakland | CB | Curtis | Marsh | |
| 2 | 18 | New York A | WR | Aldrick | Robinson | |
| ROUND 3 |
| 3 | 1 | Seattle | S | Da'Norris | Searcy | |
| 3 | 2 | St. Louis | T | James | Brewer | |
| 3 | 3 | Detroit | WR | Vincent | Brown | |
| 3 | 4 | Denver | DE | Quinton | Spears | |
| 3 | 5 | Dallas | TE | Lance | Kendricks | |
| 3 | 6 | Detroit | DE | Cameron | Heyward | |
| 3 | 7 | San Francisco | QB | Andy | Dalton | |
| 3 | 8 | Jacksonville | T | James | Carpenter | |
| 3 | 9 | Green Bay | HB | Kendall | Hunter | |
| 3 | 10 | Indianapolis | DE | Allen | Bailey | |
| 3 | 11 | San Francisco | CB | Brandon | Burton | |
| 3 | 12 | New York A | LB | Jamari | Lattimore | |
| 3 | 13 | Denver | CB | Brandon | Hogan | |
| 3 | 14 | New York A | DT | Marvin | Austin | |
| 3 | 15 | Oakland | S | Jaiquawn | Jarrett | |
| 3 | 16 | New York A | T | Chris | Harr | |
| 3 | 17 | Detroit | DT | Jarvis | Jenkins | |
| 3 | 18 | Detroit | LB | D.J. | Smith | |
| ROUND 4 |
| 4 | 1 | Seattle | DT | Andrew | Soucy | |
| 4 | 2 | Dallas | T | D.J. | Jones | |
| 4 | 3 | Baltimore | LB | Doug | Hogue | |
| 4 | 4 | Denver | K | Kai | Forbath | |
| 4 | 5 | Dallas | HB | Jacquizz | Rodgers | |
| 4 | 6 | Detroit | WR | Jeremy | Ross | |
| 4 | 7 | Jacksonville | G | Will | Rackley | |
| 4 | 8 | Dallas | LB | Mario | Harvey | |
| 4 | 9 | Jacksonville | TE | Jordan | Cameron | |
| 4 | 10 | Indianapolis | WR | Jeremy | Kerley | |
| 4 | 11 | San Francisco | TE | D.J. | Williams | |
| 4 | 12 | Dallas | WR | Jock | Sanders | |
| 4 | 13 | Detroit | FB | Owen | Marecic | |
| 4 | 14 | San Diego | DT | Kenrick | Ellis | |
| 4 | 15 | Detroit | S | Ahmad | Black | |
| 4 | 16 | San Diego | T | Mike | Smith | |
| 4 | 17 | Oakland | HB | Mikel | LeShoure | |
| 4 | 18 | New York A | K | Dan | Bailey | |
| ROUND 5 |
| 5 | 1 | Jacksonville | T | Joseph | Barksdale | |
| 5 | 2 | St. Louis | T | Mike | Ingersoll | |
| 5 | 3 | Baltimore | G | Chris | Stewart | |
| 5 | 4 | Denver | CB | Rashad | Carmichael | |
| 5 | 5 | St. Louis | DT | Terrell | McClain | |
| 5 | 6 | Detroit | CB | Cortez | Allen | |
| 5 | 7 | Kansas City | P | Ryan | Donahue | |
| 5 | 8 | Jacksonville | C | Brandon | Fusco | |
| 5 | 9 | Green Bay | DE | Greg | Romeus | |
| 5 | 10 | Indianapolis | T | J'Michael | Deane | |
| 5 | 11 | San Francisco | C | Zane | Taylor | |
| 5 | 12 | New York A | C | Kevin | Kowalski | |
| 5 | 13 | Oakland | LB | Antonio | Johnson | |
| 5 | 14 | New York A | G | Zach | Hurd | |
| 5 | 15 | Tampa Bay | TE | Charlie | Gantt | |
| 5 | 16 | San Diego | C | Stefen | Wisniewski | |
| 5 | 17 | Oakland | WR | Austin | Pettis | |
| 5 | 18 | Oakland | LB | Mason | Foster | |
| ROUND 6 |
| 6 | 1 | Seattle | LB | Colin | McCarthy | |
| 6 | 2 | St. Louis | LB | Brandon | Peguese | |
| 6 | 3 | Baltimore | QB | T.J. | Yates | |
| 6 | 4 | Denver | S | Deunta | Williams | |
| 6 | 5 | Tampa Bay | LB | Greg | Jones | |
| 6 | 6 | Jacksonville | DE | Gabe | Miller | |
| 6 | 7 | Kansas City | TE | Ben | Cleveland | |
| 6 | 8 | Jacksonville | LB | Casey | Matthews | |
| 6 | 9 | Green Bay | LB | Obi | Ezeh | |
| 6 | 10 | Indianapolis | HB | Matt | Asiata | |
| 6 | 11 | San Francisco | S | Jermale | Hines | |
| 6 | 12 | New York A | FB | Dan | Dierking | |
| 6 | 13 | Oakland | CB | Marcell | Gipson | |
| 6 | 14 | Tampa Bay | DT | Sealver | Siliga | |
| 6 | 15 | Washington | WR | Perry | Baker | |
| 6 | 16 | San Diego | DE | Junior | Tui'one | |
| 6 | 17 | Detroit | CB | Niles | Brinkley | |
| 6 | 18 | Tampa Bay | HB | Alex | Green | |
| ROUND 7 |
| 7 | 1 | Seattle | T | Derek | Newton | |
| 7 | 2 | St. Louis | CB | Richard | Sherman | |
| 7 | 3 | Baltimore | S | Mistral | Raymond | |
| 7 | 4 | Denver | LB | Lawrence | Wilson | |
| 7 | 5 | Dallas | S | Mark | LeGree | |
| 7 | 6 | Detroit | CB | Devon | Torrence | |
| 7 | 7 | Kansas City | G | Austin | Emerson | |
| 7 | 8 | Washington | FB | Anthony | Sherman | |
| 7 | 9 | Green Bay | HB | Stevan | Ridley | |
| 7 | 10 | Indianapolis | TE | Julius | Thomas | |
| 7 | 11 | Green Bay | TE | Collin | Franklin | |
| 7 | 12 | New York A | QB | Ricky | Stanzi | |
| 7 | 13 | Jacksonville | P | Matt | Bosher | |
| 7 | 14 | Tampa Bay | HB | John | Goebel | |
| 7 | 15 | Washington | T | Lee | Ziemba | |
| 7 | 16 | San Diego | TE | Kyle | Adams | |
| 7 | 17 | Detroit | DT | Saia | Falahola | |
| 7 | 18 | New York N | FB | Kyle | Nelson | |